Psychedelic Mushrooms in Oregon: a prologue

In 2020, Oregon voters approved a first-in-the-nation framework for legally consuming psilocybin-containing (“magic”) mushrooms.

After a robust rulemaking process, people in Oregon can now access Psilocybin Services in the state, where they choose a licensed facilitator who works with them through a preparation session, an administration session at a licensed service center, and an optional integration session.

Prototype comic for outreach project with neuroscientist Luca Mazzucato at the University of Oregon. This one is about Oregon’s psilocybin services, detailing what exactly Oregonians voted on, and how the ballot measure has been implemented so far.

Written May 2023. Your local laws and regulations may have changed since the comic’s release.

This comic has 15 more pages. You can currently read the whole thing on the Oregon Health Authority’s website. (Not because I made it for the OHA, but they were kind enough to post it there.)

The next chapter of the project will be a mycology 101 situation.

Following are all the citations for the full comic (because written citations are good and all, but links to citations are better).

Page One:

The QR code leads to ORS 475A

The final adopted rules can be found on the Oregon Secretary of State website, under the Oregon Health Authority Public Health Division Chapter 333, Division 333.

Page Two:

More about M110 is at the Oregon Health Authority’s Drug Addiction Treatment and Recovery Act web page

Page Three

The QR code leads to Griffiths, Roland R et al. “Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.” Journal of psychopharmacology (Oxford, England) vol. 30,12 (2016): 1181-1197.

Further reading:

Davis AK, Barrett FS, May DG, et al. Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2021;78(5):481–489.

Oregon Psilocybin Advisory Board Rapid Evidence Review and Recommendations.

Page Four:

Bryan Roth, personal correspondence.

Roland Griffiths, from Michael Pollan’s How to Change Your Mind.

Monnica Williams quote from “Psychedelics and Race: A Profile of Dr. Monnica T. Williams”, written by Patricia Kubala in Society for Cultural Anthropology.

Page Seven:

Oregon Psilocybin Advisory Board Rapid Evidence Review and Recommendations, page 12 and page 27.

Page Ten:

The trials by organizations currently furthest on the path towards FDA approval, Usona’s PSIL201 trial for Major Depressive Disorder and Compass Pathways’ COMP Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression, both gave 25mg of psilocybin to trial participants.

Page Eleven:

Map of possible service center location from Psychedelic Alpha’s Oregon Psilocybin Services Act Local Jurisdiction Tracker.

Page Thirteen:

The previously mentioned Usona and Compass Pathways trials have three and two integration sessions respectively.